The Marlborough Tavern was built in 1740 at the corner of two main roadways - the Hebron-Middle Haddam Turnpike (now Route 66) and the New London Turnpike (now North and South Main Street).

Aside from serving as a tavern, it was also a post office during the 1790s and a hotel and rest area for travelers of the turnpikes during much of the 1800s. But its historic past also contains many notable people. It was the home of the Buell family who were very active in the military and served during the Revolutionary War and the War of 1812. In fact, the Elisha Buell was a contractor of muskets and created the Buell Musket, which is now a very rare antique. The tavern was also the home of Mary Hall during the very early part of the 1900s. Mary Hall is best know as Connecticut's first female attorney and the creator of the Goodwill Club of Hartford.

The third floor of the tavern also has a unique history. As sheriffs were transporting prisoners to the New Gate Prison, they would stop and rest here and place their prisoners in a holding cell on the third floor.

On September 24th, 2011, The Historic Marlborough Tavern closed its doors.